Daily Archives: October 3, 2016


White matter vs Grey Matter [Show Notes]

Basic Brain Biology

Your brain is made of cells.  Those cells are called neurons.  Neurons transmit signals in the form of electricity (aka .positive and negative charges).  One end of a neuron will build a signal or charge, and once it reaches a certain threshold, then a signal is send down the axons.

Most of the cells in your body touch and transmit signals and pass chemicals through their membranes.  Neurons do not touch.  The terminals of one will get really really close to the dendrites of another.

They’re really good at the telephone game – mostly because the body tries to minimize the number of neurons involved in passing a signal.

Axons are coated in myelin.  Myelin insulates the axon that helps the signal being sent travel faster, and prevents it from getting lost to something else touching it.  You want the signal to have to same strength when it reaches its destination as it did when it left its source.

Parts of a neuron

Dendrites: receives signals from previous neuron
Cell body: contains the nucleus and creates and translates signals
Axon: the “wire” that transmits signals
Terminals: sends signals to the next neuron

a hand-drawn sketch of a basic neuron with labeled parts. This makes up white matter and grey matter in the brain.

Grey matter – cell bodies, dendrites, and terminals
White matter – axons wrapped in myelin

Grey matter – information storage and translation
White matter – information transmission

Brain: grey matter is on the outside, white matter is on the inside
Spinal cord:  grey matter is on the inside, white matter is on the outside.

PS.  Grey?  Gray?  IDK!!!

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Music Credits:  “Radio Martini” Kevin MacLeod (incompetech.com)  Licensed under Creative Commons: By Attribution 3.0  http://creativecommons.org/licenses/by/3.0/


Meningitis [Show Notes]

Basics

Meningitis = inflammation of meninges

Generalized symptoms:  fever, headache, stiff neck, light sensitivity, confusion, lethargy, 

4 types of infectious meningitis

  1. Bacterial – we have a vaccine for that! 3-7 days; spreads in close communities (like college dorms).  Spreads through prolonged contact.  Confirmed through spinal tap and cerebrospinal fluid culture
  2. Viral – most common type; can be caused by lots of viruses: enterovirus, mumps, measles, flu, west nile.  7-10 days.  This is why I believe in vaccines!
  3. Fungal – not contagious; most common in patient with suppressed immune systems or secondary from surgery.
  4. Parasitic – Rare yet fatal.  Amoeba enters through nose from warm contaminated fresh water sources or pool, even hot springs (warm up to 115* F).  Only 31 cases in the 10 years between 2002 and 2012.  Destroys brain tissue ~ 5 days. 

Non-infectious causes:  Surgery, injury, lupus, cancer

The most important thing is that all of this be monitored by a doctor – ALWAYS!!

2 quick tests for meningitis

Kernig’s sign 

Brudzinski’s sign

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Music Credits:  “Radio Martini” Kevin MacLeod (incompetech.com)  Licensed under Creative Commons: By Attribution 3.0  http://creativecommons.org/licenses/by/3.0/