seizures


Now You See It [Show Notes]

Occipital Lobe Review

A brain lesion is a place in the brain that doesn’t fire when it should or fires sporadically when it shouldn’t.  Occipital lobe lesions can lead to hallucinations that range from amorphous to extremely detailed.

Field blindness: a lesion causes the occipital lobe to not translate the information from one or more spots of the visual map (your whole view).  Blind spots (round) or visual cuts (lines).

Photosensitivity seizures: seizures triggered by visual overstimulation.  Even though stereotypical in different forms of entertainment, these only accounts for about 10% of seizure triggers.  Seizures triggered by visual stimulation can range from mild to severe.

Certain types of blindness can be rooted in translation problems in the brain, rather than reception problems in the eyeball.

Lesions in the occipital-temporal-parietal junction:

  • Color agnosia: can see the colors but can’t recall the names; simplified colors (all greens appear to be the same green)
  • Movement agnosia: think weeping angels (things only move to a new position when you’re not looking at it) or moving items appear blurry
  • Agraphia: unable to communicate in writin

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Brain Lesions [Show Notes]

Basics

Brain lesion = a group of brain cells that look different from surrounding cells on a brain scan

Dark lesions – an area where the brain cells are missing or an area where signal is not firing (damaged cells)
Light lesions – an area where the signals are firing at the wrong times (like a shorted out wire). Seizure – when the brain fires the electricity at the wrong time.

Lesions around the brain

A lesion in the Parietal lobe could affect how the body translates sensations (i.e. pain).  These lesions are usually caused by injury or stroke.

If there is a lesion in the optical lobe of the brain (the area that “sees” what your eyes are looking at), then the signals from the eyes may not come through, and therefore the parietal cannot help map what you were looking at once it’s not there anymore.

Sensory seizures – feeling things on you or touching you that aren’t really there. (unsure if this is related to the auras that come before migraines).  No medication necessary.

Extinction phenomenon:  thinking that a sensation stopped before it really did.  You body can’t translate two messages of the same type at the same time.  Like when you try to locate the same place on each side of your body (i.e. making pigtails even).

Some Big Words

Dyslexia:  can be related to written language, spoken language, or any other message being translated as language

Dysphasia or Aphasia:  mixed up or missing words

Dyscalculia:  it’s hard to math.  Difficulty estimating distances, spacial mapping, and time passage.  Dana White of A Slob Comes Clean talks about TPAD (Time Passage Awareness Disorder)

Apraxia:  unable plan what you want your body to do in order to make your body do it.  The deeper the path the more “natural”  the action is. Muscle memory is just an extremely well-developed motor path, so that you can even not do that action for a while, and when you do it again, you don’t have to “relearn” it. If this is caused by a stroke, therapy can help try and re-route the information. Apraxia can affect gross motor movements (large movements with your body) – aka global apraxia, or it can affect speech motor planning.

Gerstmann Syndrome: no motor path to write, or math, or to feel and use your fingers as separate digits. Also involves a left-right mix up.  In adults, it’s the results of a stroke.  In kids, they have not a clue. Therapy can help kids get past the motor issues, but not the mathing issues.

Constructional apraxia:  know how blocks should fit together, but the brain can’t make their body build it.
Dressing apraxia: know how clothes should be worn and where it goes, but the brain can’t make the body dress itself.  This shows up in dementia and Alzheimer’s a lot.

Amorphosynthesis – your brain is not aware of some part of your body.  Usually a symptom after as stroke.

Another symptom of a stroke is when a person is unaware of one-half of their visual field.  So they will only write on one half of the paper (the half they can see) or read only one half of the page of a book.

Anosognosia – a person is not aware that they have a disorder, disease, or disability.   This is not just denial.  The area of their brain that would recognize “I’m sick” or “I’m hurt” doesn’t work.

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On the tip of my brain [Show Notes]

Recap

Frontal Lobe

  • Motor cortex – voluntary muscle movements, including the muscles that control speech
  • Language translation
  • Prefrontal cortex – personality, judgment

Dopamine

The main chemical, or neurotransmitter, that functions in the frontal lobe is dopamine.

Reward System and Addiction

  • Dopamine is part of your brain’s reward system.
    • So think about when you get a Facebook notification…. dopamine is released in your brain, and your brain really likes how dopamine makes it feel.  Feels good!  So you’re brain will help you pay more attention to the things that will get you more dopamine (that’s why a 5-second Facebook glance can turn into 30 minutes).  This also means that dopamine is involved in your attention span.
    • Some newer studies are looking at dopamine’s effect on addiction.
    • The problem is that it requires increasing levels of “excitement” for your brain to receive the same level of dopamine as the very first time.  This is why people with devastating addictions end up on a downward spiral of ruin.

Memories

  • Dopamine is also involved in short-term memory, especially in complex or cascading tasks (where you have to remember a thing from Step A to complete Step B) in your prefrontal cortex.
    • Diseases that take away short-term memory:  Dementia (general or Parkinson’s-related), Alzheimers.
    • Dopamine is being studied in how it related to dementia and Alzheimer’s.  It’s effects are already known in Parkinson’s disease.
    • To form memories, your brain has to access the same information over and over again (like a smooth, speedy highway).  A road only traveled once, is not easy to travel again, especially if there’s a long period of time between trips down that road.  So in diseases that involve brain cell death, there becomes less and less routes to take to the same memory.  Thus, the older memories are the last to go because they have the most access routes.

Planing

  • Dopamine is responsible for your planning and motivation mechanisms.  If I make a plan and carry out the plan, the reward of dopamine is the outcome.

A New Discovery

They’ve discovered a genetic component that affects the shape of the dopamine receptors.

scanned-image

These cells in your brain don’t actually touch each other.  The terminals spit out dopamine, and it floats in the space and hopefully comes in contact with the next cell’s dendrites.  The dendrites have dopamine-shaped keyholes, and the dopamine should fit in the keyholes perfectly.  But they have discovered that a genetic component affects the keyhole shapes, and this make be a root cause for schizophrenia and attention deficits.

If you think about it, the classic symptoms of schizophrenia – paranoia, anxiety, hallucinations, split personalities – most things affected in your prefrontal cortex.  So if the dopamine receptors are “broken” in this area of your frontal lobe, you can see how there could be a dysfunction.  And this is produced at the genetic level.  Science is still learning about this…

Stroke

Strokes or brain injury in this area of your brain can affect personality. These parts of your brain don’t grow back! Some issues related to the speech motor area of the brain (Broca’s area).  Stuttering (clinically diagnosed) is a misfire in the motor planning part of speech.  Aphasia (loss of words) – part of you brain knows the word but you can’t seem to get it out of your mouth.  Strokes in this area can cause some strange effects in the loss of words.

Seizures

There is also a type of epilepsy (seizures).  Seizures are a misfire or a short in the electrical signals of the brain.  Seizures in the frontal lobe can possibly affect memory (epilepsy-related amnesia).  Must be diagnosed by a neurologist.

Story Time

Back in the day, there was a guy named Pheneas Gage who worked on the railroad.  An accident involving dynamite and a railroad spike, led to a major head injury and an altered personality!

We rub our forehead when we’re trying to remember something because that’s where our short-term memory is.

#RealTalk

Cynthia doesn’t have that many Facebook friends!

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